With increasing age, a decrease in volume in the facial area and a slackening of the skin can be observed. In addition to the lack of volume, wrinkles and dents often appear on the facial surface. While decades ago a facelift was the only way to achieve a more youthful and fresh appearance, over time, methods have been developed to rejuvenate the aging face. Nowadays it is possible to restore the volume permanently by transplanting one’s own fat and lining facial areas, and to compensate for wrinkles and unevenness. Through the simultaneous transplantation of pluripotent stem cells in the fat tissue, even outdated structures are broken down and new connective tissue (collagen and elastic fibres) is produced.